A common assumption in the literature on information diffusion is that populations are homogeneous regarding individuals' information acquisition and propagation process: Individuals update their informed and actively communicating state either through imitation (simple contagion) or peer influence (complex contagion). Here, we study the impact of the mixing and placement of individuals with different update processes on how information cascades in social networks. We consider Simple Spreaders, which take information from a random neighbor and communicate it, and Threshold-based Spreaders, which require a threshold number of active neighbors to change their state to active communication. Even though, in a population made exclusively of Simple Spreaders, information reaches all elements of any (connected) network, we show that, when Simple and Threshold-based Spreaders coexist and occupy random positions in a social network, the number of Simple Spreaders systematically amplifies the cascades only in degree heterogeneous networks (exponential and scale-free). In random and modular structures, this cascading effect originated by Simple Spreaders only exists above a critical mass of these individuals. In contrast, when Threshold-based Spreaders are assorted preferentially in the nodes with a higher degree, the cascading effect of Simple Spreaders vanishes, and the spread of information is drastically impaired. Overall, the study highlights the significance of the strategic placement of different roles in networked structures, with Simple Spreaders driving widespread cascades in heterogeneous networks and Threshold-based Spreaders playing a critical regulatory role in information spread with a tunable effect based on the threshold value.