Over the past few years, we have observed different media outlets' attempts to shift public opinion by framing information to support a narrative that facilitate their goals. Malicious users referred to as "pathogenic social media" (PSM) accounts are more likely to amplify this phenomena by spreading misinformation to viral proportions. Understanding the spread of misinformation from account-level perspective is thus a pressing problem. In this work, we aim to present a feature-driven approach to detect PSM accounts in social media. Inspired by the literature, we set out to assess PSMs from three broad perspectives: (1) user-related information (e.g., user activity, profile characteristics), (2) source-related information (i.e., information linked via URLs shared by users) and (3) content-related information (e.g., tweets characteristics). For the user-related information, we investigate malicious signals using causality analysis (i.e., if user is frequently a cause of viral cascades) and profile characteristics (e.g., number of followers, etc.). For the source-related information, we explore various malicious properties linked to URLs (e.g., URL address, content of the associated website, etc.). Finally, for the content-related information, we examine attributes (e.g., number of hashtags, suspicious hashtags, etc.) from tweets posted by users. Experiments on real-world Twitter data from different countries demonstrate the effectiveness of the proposed approach in identifying PSM users.