Business Process Simulation (BPS) is an approach to analyze the performance of business processes under different scenarios. For example, BPS allows us to estimate what would be the cycle time of a process if one or more resources became unavailable. The starting point of BPS is a process model annotated with simulation parameters (a BPS model). BPS models may be manually designed, based on information collected from stakeholders and empirical observations, or automatically discovered from execution data. Regardless of its origin, a key question when using a BPS model is how to assess its quality. In this paper, we propose a collection of measures to evaluate the quality of a BPS model w.r.t. its ability to replicate the observed behavior of the process. We advocate an approach whereby different measures tackle different process perspectives. We evaluate the ability of the proposed measures to discern the impact of modifications to a BPS model, and their ability to uncover the relative strengths and weaknesses of two approaches for automated discovery of BPS models. The evaluation shows that the measures not only capture how close a BPS model is to the observed behavior, but they also help us to identify sources of discrepancies.