JavaScript is an increasingly popular language for server-side development, thanks in part to the Node.js runtime environment and its vast ecosystem of modules. With the Node.js package manager npm, users are able to easily include external modules as dependencies in their projects. However, npm installs modules with all of their functionality, even if only a fraction is needed, which causes an undue increase in code size. Eliminating this unused functionality from distributions is desirable, but the sound analysis required to find unused code is difficult due to JavaScript's extreme dynamicity. We present a fully automatic technique that identifies unused code by constructing static or dynamic call graphs from the application's tests, and replacing code deemed unreachable with either file- or function-level stubs. If a stub is called, it will fetch and execute the original code on-demand, thus relaxing the requirement that the call graph be sound. The technique also provides an optional guarded execution mode to guard application against injection vulnerabilities in untested code that resulted from stub expansion. This technique is implemented in an open source tool called Stubbifier, which supports the ECMAScript 2019 standard. In an empirical evaluation on 15 Node.js applications and 75 clients of these applications, Stubbifier reduced application size by 56% on average while incurring only minor performance overhead. The evaluation also shows that Stubbifier's guarded execution mode is capable of preventing several known injection vulnerabilities that are manifested in stubbed-out code. Finally, Stubbifier can work alongside bundlers, popular JavaScript tools for bundling an application with its dependencies. For the considered subject applications, we measured an average size reduction of 37% in bundled distributions.