Rust is an emerging, strongly-typed programming language focusing on efficiency and memory safety. With increasing projects adopting Rust, knowing how to use Unsafe Rust is crucial for Rust security. We observed that the description of safety requirements needs to be unified in Unsafe Rust programming. Current unsafe API documents in the standard library exhibited variations, including inconsistency and insufficiency. To enhance Rust security, we suggest unsafe API documents to list systematic descriptions of safety requirements for users to follow. In this paper, we conducted the first comprehensive empirical study on safety requirements across unsafe boundaries. We studied unsafe API documents in the standard library and defined 19 safety properties (SP). We then completed the data labeling on 416 unsafe APIs while analyzing their correlation to find interpretable results. To validate the practical usability and SP coverage, we categorized existing Rust CVEs until 2023-07-08 and performed a statistical analysis of std unsafe API usage toward the crates.io ecosystem. In addition, we conducted a user survey to gain insights into four aspects from experienced Rust programmers. We finally received 50 valid responses and confirmed our classification with statistical significance.