Automated translation of legacy C code into Rust aims to ensure memory safety while reducing the burden of manual migration. Early approaches in code translation rely on static rule-based methods, but they suffer from limited coverage due to dependence on predefined rule patterns. Recent works regard the task as a sequence-to-sequence problem by leveraging large language models (LLMs). Although these LLM-based methods are capable of reducing unsafe code blocks, the translated code often exhibits issues in following Rust rules and maintaining semantic consistency. On one hand, existing methods adopt a direct prompting strategy to translate the C code, which struggles to accommodate the syntactic rules between C and Rust. On the other hand, this strategy makes it difficult for LLMs to accurately capture the semantics of complex code. To address these challenges, we propose IRENE, an LLM-based framework that Integrates RulEs aNd sEmantics to enhance translation. IRENE consists of three modules: 1) a rule-augmented retrieval module that selects relevant translation examples based on rules generated from a static analyzer developed by us, thereby improving the handling of Rust rules; 2) a structured summarization module that produces a structured summary for guiding LLMs to enhance the semantic understanding of C code; 3) an error-driven translation module that leverages compiler diagnostics to iteratively refine translations. We evaluate IRENE on two datasets (xCodeEval, a public dataset, and HW-Bench, an industrial dataset provided by Huawei) and eight LLMs, focusing on translation accuracy and safety.