Context: Safety analysis is a predominant activity in developing safety-critical systems. It is a highly cooperative task among multiple functional departments due to increasingly sophisticated safety-critical systems and close-knit development processes. Communication occurs pervasively. Motivation: Effective communication channels among multiple functional departments influence safety analysis, quality as well as a safe product delivery. However, the use of communication channels during safety analysis is sometimes arbitrary and poses challenges. Objective: Investige the existing communication channels, their usage frequencies, their purposes and challenges during safety analysis in industry.. Method: Multiple case study of experts (survey: 39, interview: 21) in safety-critical companies including software developers, quality engineers and functional safety managers. Direct observations and documentation review were also conducted. Results: Popular communication channels during safety analysis include formal meetings, project coordination tools, documentation and telephone. Email, personal discussion, training, internal communication software and boards are also in use. Training involving safety analysis happens 1-4 times per year, while other aforementioned communication channels happen ranges from 1-4 times per day to 1-4 times per month. We summarise 28 purposes for these communication channels. Communication happens mostly for the purpose of clarifying safety requirements, fixing temporary problems, conflicts and obstacles and sharing safety knowledge. The top challenges are reported. Conclusion: During safety analysis, to use communication channels effectively and avoid challenges, a clear purpose of communication during safety analysis should be established at the beginning. To derive countermeasures of fixing the top 10 challenges are potential next steps.