Cloud compute adoption has been growing since its inception in the early 2000's with estimates that the size of this market in terms of worldwide spend will increase from \$700 billion in 2021 to \$1.3 trillion in 2025. While there is a significant research activity in many areas of cloud computing technologies, we see little attention being paid to advancing software engineering practices needed to support the current and next generation of cloud native applications. By cloud native, we mean software that is designed and built specifically for deployment to a modern cloud platform. This paper frames the landscape of Cloud Native Software Engineering from a practitioners standpoint, and identifies several software engineering research opportunities that should be investigated. We cover specific engineering challenges associated with software architectures commonly used in cloud applications along with incremental challenges that are expected with emerging IoT/Edge computing use cases.