Configuration tuning for large software systems is generally challenging due to the complex configuration space and expensive performance evaluation. Most existing approaches follow a two-phase process, first learning a regression-based performance prediction model on available samples and then searching for the configurations with satisfactory performance using the learned model. Such regression-based models often suffer from the scarcity of samples due to the enormous time and resources required to run a large software system with a specific configuration. Moreover, previous studies have shown that even a highly accurate regression-based model may fail to discern the relative merit between two configurations, whereas performance comparison is actually one fundamental strategy for configuration tuning. To address these issues, this paper proposes CM-CASL, a Comparison-based performance Modeling approach for software systems via Collaborative Active and Semisupervised Learning. CM-CASL learns a classification model that compares the performance of two given configurations, and enhances the samples through a collaborative labeling process by both human experts and classifiers using an integration of active and semisupervised learning. Experimental results demonstrate that CM-CASL outperforms two state-of-the-art performance modeling approaches in terms of both classification accuracy and rank accuracy, and thus provides a better performance model for the subsequent work of configuration tuning.