Safety assurance is of paramount importance across various domains, including automotive, aerospace, and nuclear energy, where the reliability and acceptability of mission-critical systems are imperative. This assurance is effectively realized through the utilization of Safety Assurance Cases. The use of safety assurance cases allows for verifying the correctness of the created systems capabilities, preventing system failure. The latter may result in loss of life, severe injuries, large-scale environmental damage, property destruction, and major economic loss. Still, the emergence of complex technologies such as cyber-physical systems (CPSs), characterized by their heterogeneity, autonomy, machine learning capabilities, and the uncertainty of their operational environments poses significant challenges for safety assurance activities. Several papers have tried to propose solutions to tackle these challenges, but to the best of our knowledge, no secondary study investigates the trends, patterns, and relationships characterizing the safety case scientific literature. This makes it difficult to have a holistic view of the safety case landscape and to identify the most promising future research directions. In this paper, we, therefore, rely on state-of-the-art bibliometric tools(e.g., VosViewer) to conduct a bibliometric analysis that allows us to generate valuable insights, identify key authors and venues, and gain a birds eye view of the current state of research in the safety assurance area. By revealing knowledge gaps and highlighting potential avenues for future research, our analysis provides an essential foundation for researchers, corporate safety analysts, and regulators seeking to embrace or enhance safety practices that align with their specific needs and objectives.