Cross-Project Defect Prediction (CPDP), which borrows data from similar projects by combining a transfer learner with a classifier, have emerged as a promising way to predict software defects when the available data about the target project is insufficient. How-ever, developing such a model is challenge because it is difficult to determine the right combination of transfer learner and classifier along with their optimal hyper-parameter settings. In this paper, we propose a tool, dubbedBiLO-CPDP, which is the first of its kind to formulate the automated CPDP model discovery from the perspective of bi-level programming. In particular, the bi-level programming proceeds the optimization with two nested levels in a hierarchical manner. Specifically, the upper-level optimization routine is designed to search for the right combination of transfer learner and classifier while the nested lower-level optimization routine aims to optimize the corresponding hyper-parameter settings.To evaluateBiLO-CPDP, we conduct experiments on 20 projects to compare it with a total of 21 existing CPDP techniques, along with its single-level optimization variant and Auto-Sklearn, a state-of-the-art automated machine learning tool. Empirical results show that BiLO-CPDP champions better prediction performance than all other 21 existing CPDP techniques on 70% of the projects, while be-ing overwhelmingly superior to Auto-Sklearn and its single-level optimization variant on all cases. Furthermore, the unique bi-level formalization inBiLO-CPDP also permits to allocate more budget to the upper-level, which significantly boosts the performance.