Modern satellite based experiments are often very complex real-time systems, composed by flight and ground segments, that have challenging resource related constraints, in terms of size, weight, power, requirements for real-time response, fault tolerance, and specialized input/output hardware-software, and they must be certified to high levels of assurance. Hardware-software data processing systems have to be responsive to system degradation and to changes in the data acquisition modes, and actions have to be taken to change the organization of the mission operations. A big research & develop effort in a team composed by scientists and technologists can lead to produce software systems able to optimize the hardware to reach very high levels of performance or to pull degraded hardware to maintain satisfactory features. We'll show real-life examples describing a system, processing the data of a X-Ray detector on satellite-based mission in spinning mode.