Cyber-Physical Systems (CPSs) combine software and physical components. These systems are widely applied in society within many domains, including the automotive, aerospace, railway, etc. Testing these systems is extremely challenging, therefore, it has attracted significant attention from the research community. A driving CPS testing technique in industry is simulation-based testing. However, this poses significant challenges. In this new-idea paper we present a novel approach to enhance the testing processes of CPSs. This novel approach is motivated with examples and open questions.