An interpolation method for region-to-region acoustic transfer functions (ATFs) based on kernel ridge regression with an adaptive kernel is proposed. Most current ATF interpolation methods do not incorporate the acoustic properties for which measurements are performed. Our proposed method is based on a separate adaptation of directional weighting functions to directed and residual reverberations, which are used for adapting kernel functions. Thus, the proposed method can not only impose constraints on fundamental acoustic properties, but can also adapt to the acoustic environment. Numerical experimental results indicated that our proposed method outperforms the current methods in terms of interpolation accuracy, especially at high frequencies.