Meaningful speech assessment is vital in clinical phonetics and therapy monitoring. This study examined the link between perceptual speech assessments and objective acoustic measures in a large head and neck cancer (HNC) dataset. Trained listeners provided ratings of intelligibility, articulation, voice quality, phonation, speech rate, nasality, and background noise on speech. Strong correlations were found between subjective intelligibility, articulation, and voice quality, likely due to a shared underlying cause of speech symptoms in our speaker population. Objective measures of intelligibility and speech rate aligned with their subjective counterpart. Our results suggest that a single intelligibility measure may be sufficient for the clinical monitoring of speakers treated for HNC using concomitant chemoradiation.