Turn-taking has played an essential role in structuring the regulation of a conversation. The task of identifying the main speaker (who is properly taking his/her turn of speaking) and the interrupters (who are interrupting or reacting to the main speaker's utterances) remains a challenging task. Although some prior methods have partially addressed this task, there still remain some limitations. Firstly, a direct association of Audio and Visual features may limit the correlations to be extracted due to different modalities. Secondly, the relationship across temporal segments helping to maintain the consistency of localization, separation, and conversation contexts is not effectively exploited. Finally, the interactions between speakers that usually contain the tracking and anticipatory decisions about the transition to a new speaker are usually ignored. Therefore, this work introduces a new Audio-Visual Transformer approach to the problem of localization and highlighting the main speaker in both audio and visual channels of a multi-speaker conversation video in the wild. The proposed method exploits different types of correlations presented in both visual and audio signals. The temporal audio-visual relationships across spatial-temporal space are anticipated and optimized via the self-attention mechanism in a Transformerstructure. Moreover, a newly collected dataset is introduced for the main speaker detection. To the best of our knowledge, it is one of the first studies that is able to automatically localize and highlight the main speaker in both visual and audio channels in multi-speaker conversation videos.