Urgently needed generalizable robot object interaction and manipulation requires high-quality Cross-Category object perception. As a pioneer of this area, Generalizable and Actionable Parts (GAParts) understanding has attracted increasing attention from relevant researchers. However, most recent works either have insufficient design regarding the symmetry issue or require rich symmetry annotation, which severely impedes precise GAPart pose estimation in data-lacking scenarios. In this paper, we propose SAFAG, a novel Symmetry Annotation-Free framework for Generalizable and Actionable Parts Pose Estimation. Specifically, we suggest a stepwise refinement two-stage framework for candidate-to-final quaternion regression, and tackle the symmetry prediction as a probability distribution problem with self-supervised learning strategy. The experimental results demonstrate the superior performance and robustness of our SAFAG. We believe that our work has the enormous potential to be applied in many areas of embodied AI system.