In the prior literature on multi-agent area defense games, the assignments of the defenders to the attackers are done based on a cost metric associated only with the interception of the attackers. In contrast to that, this paper presents an Inter-Defender Collision-Aware Interception Strategy (IDCAIS) for defenders to intercept attackers in order to defend a protected area, such that the defender-to-attacker assignment protocol not only takes into account an interception-related cost but also takes into account any possible future collisions among the defenders on their optimal interception trajectories. In particular, in this paper, the defenders are assigned to intercept attackers using a mixed-integer quadratic program (MIQP) that: 1) minimizes the sum of times taken by defenders to capture the attackers under time-optimal control, as well as 2) helps eliminate or delay possible future collisions among the defenders on the optimal trajectories. To prevent inevitable collisions on optimal trajectories or collisions arising due to time-sub-optimal behavior by the attackers, a minimally augmented control using exponential control barrier function (ECBF) is also provided. Simulations show the efficacy of the approach.