Differential-driven wheeled robots (DWR) represent the quintessential type of mobile robots and find extensive appli- cations across the robotic field. Most high-performance control approaches for DWR explicitly utilize the linear and angular velocities of the trajectory as control references. However, existing research on time-optimal path parameterization (TOPP) for mobile robots usually neglects the angular velocity and joint vel- ocity constraints, which can result in degraded control perfor- mance in practical applications. In this article, a systematic and practical TOPP algorithm named TOPP-DWR is proposed for DWR and other mobile robots. First, the non-uniform B-spline is adopted to represent the initial trajectory in the task space. Second, the piecewise-constant angular velocity, as well as joint velocity, linear velocity, and linear acceleration constraints, are incorporated into the TOPP problem. During the construction of the optimization problem, the aforementioned constraints are uniformly represented as linear velocity constraints. To boost the numerical computational efficiency, we introduce a slack variable to reformulate the problem into second-order-cone programming (SOCP). Subsequently, comparative experiments are conducted to validate the superiority of the proposed method. Quantitative performance indexes show that TOPP-DWR achieves TOPP while adhering to all constraints. Finally, field autonomous navigation experiments are carried out to validate the practicability of TOPP-DWR in real-world applications.