Current mobile manipulation research predominantly follows an instruction-driven paradigm, where agents rely on predefined textual commands to execute tasks. However, this setting confines agents to a passive role, limiting their autonomy and ability to react to dynamic environmental events. To address these limitations, we introduce sound-triggered mobile manipulation, where agents must actively perceive and interact with sound-emitting objects without explicit action instructions. To support these tasks, we develop Habitat-Echo, a data platform that integrates acoustic rendering with physical interaction. We further propose a baseline comprising a high-level task planner and low-level policy models to complete these tasks. Extensive experiments show that the proposed baseline empowers agents to actively detect and respond to auditory events, eliminating the need for case-by-case instructions. Notably, in the challenging dual-source scenario, the agent successfully isolates the primary source from overlapping acoustic interference to execute the first interaction, and subsequently proceeds to manipulate the secondary object, verifying the robustness of the baseline.