Driving simulators are increasingly used in research and development. However, simulators often cause motion sickness due to downscaled motion and unscaled veridical visuals. In this paper, a motion cueing algorithm is proposed that reduces motion sickness as predicted by the subjective vertical conflict (SVC) model using model predictive control (MPC). Both sensory conflict and specific force errors are penalised in the cost function, allowing the algorithm to jointly optimise fidelity and comfort. Human-in-the-loop experiments were conducted to compare four simulator motion settings: two variations of our MPC-based algorithm, one focused on pure specific force tracking and the second compromising specific force tracking and motion sickness minimisation, as well as reference adaptive washout and no motion cases. The experiments were performed on a hexapod driving simulator with participants exposed to passive driving. Experimental motion sickness results closely matched the sickness model predictions. As predicted by the model, the no motion condition yielded the lowest sickness levels. However, it was rated lowest in terms of fidelity. The compromise solution reduced sickness by over 50% (average MISC level 3 to 1.5) compared to adaptive washout and the algorithm focusing on specific force tracking, without any significant reduction in fidelity rating. The proposed approach for developing MCA that takes into account both the simulator dynamics and time evolution of motion sickness offers a significant advancement in achieving an optimal control of motion sickness and specific force recreation in driving simulators, supporting broader simulator use.