Prompt and accurate precipitation forecast is very important for development management of regional water resource, flood disaster prevention and people's daily activity and production plan; however, non-linear and nonstationary characteristics of precipitation data and noise seriously affect forecast accuracy. This paper combines multicellular gene expression programming with more powerful function mining ability and wavelet analysis with more powerful denoising and extracting data fine feature capability for precipitation forecast modeling, proposing to estimate meteorological precipitation with WTGEPRP algorithm. Comparative result for simulation experiment with actual precipitation data in Zhengzhou, Nanning and Melbourne in Australia indicated that: fitting and forecasting performance of WTGEPRP algorithm is better than the algorithm Multicellular Gene Expression Programming-based Hybrid Model for Precipitation Prediction Coupled with EMD, Supporting Vector Regression, BP Neural Network, Multicellular Gene Expression Programming and Gene Expression Programming, and has good application prospect.