The maximum k-plex problem is a computationally complex problem, which emerged from graph-theoretic social network studies. This paper presents an effective hybrid local search for solving the maximum k-plex problem that combines the recently proposed breakout local search algorithm with a reinforcement learning strategy. The proposed approach includes distinguishing features such as: a unified neighborhood search based on the swapping operator, a distance-and-quality reward for actions and a new parameter control mechanism based on reinforcement learning. Extensive experiments for the maximum k-plex problem (k = 2, 3, 4, 5) on 80 benchmark instances from the second DIMACS Challenge demonstrate that the proposed approach can match the best-known results from the literature in all but four problem instances. In addition, the proposed algorithm is able to find 32 new best solutions.