This study presents domain-informed genetic superposition programming (DIGSP), a symbolic regression framework tailored for engineering systems governed by separable physical mechanisms. DIGSP partitions the input space into domain-specific feature subsets and evolves independent genetic programming (GP) populations to model material-specific effects. Early evolution occurs in isolation, while ensemble fitness promotes inter-population cooperation. To enable symbolic superposition, an adaptive hierarchical symbolic abstraction mechanism (AHSAM) is triggered after stagnation across all populations. AHSAM performs analysis of variance- (ANOVA) based filtering to identify statistically significant individuals, compresses them into symbolic constructs, and injects them into all populations through a validation-guided pruning cycle. The DIGSP is benchmarked against a baseline multi-gene genetic programming (BGP) model using a dataset of steel fiber-reinforced concrete (SFRC) beams. Across 30 independent trials with 65% training, 10% validation, and 25% testing splits, DIGSP consistently outperformed BGP in training and test root mean squared error (RMSE). The Wilcoxon rank-sum test confirmed statistical significance (p < 0.01), and DIGSP showed tighter error distributions and fewer outliers. No significant difference was observed in validation RMSE due to limited sample size. These results demonstrate that domain-informed structural decomposition and symbolic abstraction improve convergence and generalization. DIGSP offers a principled and interpretable modeling strategy for systems where symbolic superposition aligns with the underlying physical structure.