
























Epileptic seizure activity shows complicated dynamics in both space and time. To understand the evolution and propagation of seizures spatially extended sets of data need to be analysed. We have previously described an efficient filtering scheme using variational Laplace that can be used in the Dynamic Causal Modelling (DCM) framework [Friston, 2003] to estimate the temporal dynamics of seizures recorded using either invasive or non-invasive electrical recordings (EEG/ECoG). Spatiotemporal dynamics are modelled using a partial differential equation -- in contrast to the ordinary differential equation used in our previous work on temporal estimation of seizure dynamics [Cooray, 2016]. We provide the requisite theoretical background for the method and test the ensuing scheme on simulated seizure activity data and empirical invasive ECoG data. The method provides a framework to assimilate the spatial and temporal dynamics of seizure activity, an aspect of great physiological and clinical importance.
此内容由惯性聚合(RSS阅读器)自动聚合整理,仅供阅读参考。 原文来自 — 版权归原作者所有。