Proton nuclear magnetic resonance (1H-NMR) is a widely used tool for chemical structural analysis. However, 1H-NMR spectra suffer from natural aberrations that render computer-assisted automated identification of these spectra difficult, and at times impossible. Previous efforts have successfully implemented instrument dependent or conditional identification of these spectra. In this paper, we report the first instrument independent computer-assisted automated identification system for a group of complex carbohydrates known as the xyloglucan oligosaccharides. The developed system is also implemented on the world wide web (http://www.ccrc.uga.edu) as part of an identification package called the CCRC-Net and is intended to recognize any submitted 1H-NMR spectrum of these structures with reasonable signal-to-noise ratio, recorded on any 500 MHz NMR instrument. The system uses Artificial Neural Networks (ANNs) technology and is insensitive to the instrument and environment-dependent variations in 1H-NMR spectroscopy. In this paper, comparative results of the ANN engine versus a multidimensional Bayes' classifier is also presented.