We show that a graph with $n$ vertices and vertex cover of size $k$ has at most $4^k + n$ potential maximal cliques. We also show that for each positive integer $k$, there exists a graph with vertex cover of size $k$, $O(k^2)$ vertices, and $Ω(4^k)$ potential maximal cliques. Our results extend the results of Fomin, Liedloff, Montealegre, and Todinca [Algorithmica, 80(4):1146--1169, 2018], who proved an upper bound of $poly(n) 4^k$, but left the lower bound as an open problem.