As simulating complex biological processes become more important for modern medicine, new ways to compute this increasingly challenging data are necessary. In this paper, one of the most extensive volunteer-based distributed computing systems, called folding@home, is analyzed, and a trust-based approach is developed based upon it. Afterward, all advantages and disadvantages are presented. This approach uses trusted communities that are a subset of all available clients where they trust each other. Using such TCs, the system becomes more organic and responds better to malicious or malfunctioning clients.