Optimizing Large Language Model (LLM) inference in production systems is increasingly difficult due to dynamic workloads, stringent latency/throughput targets, and a rapidly expanding configuration space. This complexity spans not only distributed parallelism strategies (tensor/pipeline/expert) but also intricate framework-specific runtime parameters such as those concerning the enablement of CUDA graphs, available KV-cache memory fractions, and maximum token capacity, which drastically impact performance. The diversity of modern inference frameworks (e.g., TRT-LLM, vLLM, SGLang), each employing distinct kernels and execution policies, makes manual tuning both framework-specific and computationally prohibitive. We present AIConfigurator, a unified performance-modeling system that enables rapid, framework-agnostic inference configuration search without requiring GPU-based profiling. AIConfigurator combines (1) a methodology that decomposes inference into analytically modelable primitives - GEMM, attention, communication, and memory operations while capturing framework-specific scheduling dynamics; (2) a calibrated kernel-level performance database for these primitives across a wide range of hardware platforms and popular open-weights models (GPT-OSS, Qwen, DeepSeek, LLama, Mistral); and (3) an abstraction layer that automatically resolves optimal launch parameters for the target backend, seamlessly integrating into production-grade orchestration systems. Evaluation on production LLM serving workloads demonstrates that AIConfigurator identifies superior serving configurations that improve performance by up to 40% for dense models (e.g., Qwen3-32B) and 50% for MoE architectures (e.g., DeepSeek-V3), while completing searches within 30 seconds on average. Enabling the rapid exploration of vast design spaces - from cluster topology down to engine specific flags.