The goal of this paper is to understand the complexity of symmetry breaking problems, specifically maximal independent set (MIS) and the closely related $β$-ruling set problem, in two computational models suited for large-scale graph processing, namely the $k$-machine model and the graph streaming model. We present a number of results. For MIS in the $k$-machine model, we improve the $\tilde{O}(m/k^2 + Δ/k)$-round upper bound of Klauck et al. (SODA 2015) by presenting an $\tilde{O}(m/k^2)$-round algorithm. We also present an $\tildeΩ(n/k^2)$ round lower bound for MIS, the first lower bound for a symmetry breaking problem in the $k$-machine model. For $β$-ruling sets, we use hierarchical sampling to obtain more efficient algorithms in the $k$-machine model and also in the graph streaming model. More specifically, we obtain a $k$-machine algorithm that runs in $\tilde{O}(βnΔ^{1/β}/k^2)$ rounds and, by using a similar hierarchical sampling technique, we obtain one-pass algorithms for both insertion-only and insertion-deletion streams that use $O(β\cdot n^{1+1/2^{β-1}})$ space. The latter result establishes a clear separation between MIS, which is known to require $Ω(n^2)$ space (Cormode et al., ICALP 2019), and $β$-ruling sets, even for $β= 2$. Finally, we present an even faster 2-ruling set algorithm in the $k$-machine model, one that runs in $\tilde{O}(n/k^{2-ε} + k^{1-ε})$ rounds for any $ε$, $0 \le ε\le 1$.