Data-driven predictive control (DPC) has been studied and used in various scenarios, since it could generate the predicted control sequence only relying on the historical input and output data. Recently, based on cloud computing, data-driven predictive cloud control system (DPCCS) has been proposed with the advantage of sufficient computational resources. However, the existing computation mode of DPCCS is centralized. This computation mode could not utilize fully the computing power of cloud computing, of which the structure is distributed. Thus, the computation delay could not been reduced and still affects the control quality. In this paper, a novel cloud-edge collaborative containerised workflow-based DPC system with disturbance observer (DOB) is proposed, to improve the computation efficiency and guarantee the control accuracy. First, a construction method for the DPC workflow is designed, to match the distributed processing environment of cloud computing. But the non-computation overheads of the workflow tasks are relatively high. Therefore, a cloud-edge collaborative control scheme with DOB is designed. The low-weight data could be truncated to reduce the non-computation overheads. Meanwhile, we design an edge DOB to estimate and compensate the uncertainty in cloud workflow processing, and obtain the composite control variable. The UUB stability of the DOB is also proved. Third, to execute the workflow-based DPC controller and evaluate the proposed cloud-edge collaborative control scheme with DOB in the real cloud environment, we design and implement a practical workflow-based cloud control experimental system based on container technology. Finally, a series of evaluations show that, the computation times are decreased by 45.19% and 74.35% for two real-time control examples, respectively, and by at most 85.10% for a high-dimension control example.