Cloud data center capacities are over-provisioned to handle demand peaks and hardware failures which leads to low resources' utilization. One way to improve resource utilization and thus reduce the total cost of ownership is to offer unused resources (referred to as ephemeral resources) at a lower price. However, reselling resources needs to meet the expectations of its customers in terms of Quality of Service. The goal is so to maximize the amount of reclaimed resources while avoiding SLA penalties. To achieve that, cloud providers have to estimate their future utilization to provide availability guarantees. The prediction should consider a safety margin for resources to react to unpredictable workloads. The challenge is to find the safety margin that provides the best trade-off between the amount of resources to reclaim and the risk of SLA violations. Most state-of-the-art solutions consider a fixed safety margin for all types of metrics (e.g., CPU, RAM). However, a unique fixed margin does not consider various workloads variations over time which may lead to SLA violations or/and poor utilization. In order to tackle these challenges, we propose ReLeaSER, a Reinforcement Learning strategy for optimizing the ephemeral resources' utilization in the cloud. ReLeaSER dynamically tunes the safety margin at the host-level for each resource metric. The strategy learns from past prediction errors (that caused SLA violations). Our solution reduces significantly the SLA violation penalties on average by 2.7x and up to 3.4x. It also improves considerably the CPs' potential savings by 27.6% on average and up to 43.6%.