Multi-Instance GPU (MIG) is a new feature introduced by NVIDIA A100 GPUs that partitions one physical GPU into multiple GPU instances. With MIG, A100 can be the most cost-efficient GPU ever for serving Deep Neural Networks (DNNs). However, discovering the most efficient GPU partitions is challenging. The underlying problem is NP-hard; moreover, it is a new abstract problem, which we define as the Reconfigurable Machine Scheduling Problem (RMS). This paper studies serving DNNs with MIG, a new case of RMS. We further propose a solution, MIG-serving. MIG- serving is an algorithm pipeline that blends a variety of newly designed algorithms and customized classic algorithms, including a heuristic greedy algorithm, Genetic Algorithm (GA), and Monte Carlo Tree Search algorithm (MCTS). We implement MIG-serving on Kubernetes. Our experiments show that compared to using A100 as-is, MIG-serving can save up to 40% of GPUs while providing the same throughput.