A litany of theoretical and numerical results have established the sketch-and-precondition paradigm as a powerful approach to solving large linear regression problems in standard computing environments. Perhaps surprisingly, much less work has been done on understanding how sketch-and-precondition performs on graphics processing unit (GPU) systems. We address this gap by benchmarking an implementation of sketch-and-precondition based on sparse sign-sketches on single and multi-GPU systems. In doing so, we describe a novel, easily parallelized, rejection-sampling based method for generating sparse sign sketches. Our approach, which is particularly well-suited for GPUs, is easily adapted to a variety of computing environments. Taken as a whole, our numerical experiments indicate that sketch-and-precondition with sparse sign sketches is particularly well-suited for GPUs, and may be suitable for use in black-box least-squares solvers.