Entity resolution (ER) is a key data integration problem. Despite the efforts in 70+ years in all aspects of ER, there is still a high demand for democratizing ER - humans are heavily involved in labeling data, performing feature engineering, tuning parameters, and defining blocking functions. With the recent advances in deep learning, in particular distributed representation of words (a.k.a. word embeddings), we present a novel ER system, called DeepER, that achieves good accuracy, high efficiency, as well as ease-of-use (i.e., much less human efforts). For accuracy, we use sophisticated composition methods, namely uni- and bi-directional recurrent neural networks (RNNs) with long short term memory (LSTM) hidden units, to convert each tuple to a distributed representation (i.e., a vector), which can in turn be used to effectively capture similarities between tuples. We consider both the case where pre-trained word embeddings are available as well the case where they are not; we present ways to learn and tune the distributed representations. For efficiency, we propose a locality sensitive hashing (LSH) based blocking approach that uses distributed representations of tuples; it takes all attributes of a tuple into consideration and produces much smaller blocks, compared with traditional methods that consider only a few attributes. For ease-of-use, DeepER requires much less human labeled data and does not need feature engineering, compared with traditional machine learning based approaches which require handcrafted features, and similarity functions along with their associated thresholds. We evaluate our algorithms on multiple datasets (including benchmarks, biomedical data, as well as multi-lingual data) and the extensive experimental results show that DeepER outperforms existing solutions.