Storing and processing of embedding vectors by specialized Vector databases (VDBs) has become the linchpin in building modern AI pipelines. Most current VDBs employ variants of a graph-based ap- proximate nearest-neighbor (ANN) index algorithm, HNSW, to an- swer semantic queries over stored vectors. Inspite of its wide-spread use, the HNSW algorithm suffers from several issues: in-memory design and implementation, random memory accesses leading to degradation in cache behavior, limited acceleration scope due to fine-grained pairwise computations, and support of only semantic similarity queries. In this paper, we present a novel disk-based ANN index, B+ANN, to address these issues: it first partitions input data into blocks containing semantically similar items, then builds an B+ tree variant to store blocks both in-memory and on disks, and finally, enables hybrid edge- and block-based in-memory traversals. As demonstrated by our experimantal evaluation, the proposed B+ANN disk-based index improves both quality (Recall value), and execution performance (Queries per second/QPS) over HNSW, by improving spatial and temporal locality for semantic operations, reducing cache misses (19.23% relative gain), and decreasing the memory consumption and disk-based build time by 24x over the DiskANN algorithm. Finally, it enables dissimilarity queries, which are not supported by similarity-oriented ANN indices.