Intel has introduced a trusted computing technology, Intel Software Guard Extension (SGX), which provides an isolated and secure execution environment called enclave for a user program without trusting any privilege software (e.g., an operating system or a hypervisor) or firmware. Nevertheless, SGX is vulnerable to several side channel attacks (e.g. page-fault-based attack and cache-based attack). In this paper, we explore a new, yet critical side channel attack in SGX, interface-based side channel attack, which can infer the information of the enclave input data. The root cause of the interface-based side channel attack is the input dependent interface invocation information (e.g., interface information and invocation patterns) which can be observed by the untrusted privilege software can reveal the control flow in the enclave. We study the methodology which can be used to conduct the interface-based side channel attack. To illustrate the effectiveness of the interface-based side-channel attacks, we use our methodology to infer whether tracked web pages have been processed by the SGX-assisted NFV platforms and achieve the accuracy of 87.6% and recall of 76.6%. We also identify the packets which belong to the tracked web pages, with the accuracy of 67.9%and recall of 71.1%. We finally propose some countermeasures to defense the interface-based side channel attack in SGX-assisted applications.