In spite that Federated Learning (FL) is well known for its privacy protection when training machine learning models among distributed clients collaboratively, recent studies have pointed out that the naive FL is susceptible to gradient leakage attacks. In the meanwhile, Differential Privacy (DP) emerges as a promising countermeasure to defend against gradient leakage attacks. However, the adoption of DP by clients in FL may significantly jeopardize the model accuracy. It is still an open problem to understand the practicality of DP from a theoretic perspective. In this paper, we make the first attempt to understand the practicality of DP in FL through tuning the number of conducted iterations. Based on the FedAvg algorithm, we formally derive the convergence rate with DP noises in FL. Then, we theoretically derive: 1) the conditions for the DP based FedAvg to converge as the number of global iterations (GI) approaches infinity; 2) the method to set the number of local iterations (LI) to minimize the negative influence of DP noises. By further substituting the Laplace and Gaussian mechanisms into the derived convergence rate respectively, we show that: 3) The DP based FedAvg with the Laplace mechanism cannot converge, but the divergence rate can be effectively prohibited by setting the number of LIs with our method; 4) The learning error of the DP based FedAvg with the Gaussian mechanism can converge to a constant number finally if we use a fixed number of LIs per GI. To verify our theoretical findings, we conduct extensive experiments using two real-world datasets. The results not only validate our analysis results, but also provide useful guidelines on how to optimize model accuracy when incorporating DP into FL