The Artificial intelligence in critical sectors-healthcare, finance, and public safety-has made system integrity paramount for maintaining societal trust. Current verification methods for AI systems lack comprehensive lifecycle assurance, creating significant vulnerabilities in deployment of both powerful and trustworthy AI. This research introduces Meta-Sealing, a cryptographic framework that fundamentally changes integrity verification in AI systems throughout their operational lifetime. Meta-Sealing surpasses traditional integrity protocols through its implementation of cryptographic seal chains, establishing verifiable, immutable records for all system decisions and transformations. The framework combines advanced cryptography with distributed verification, delivering tamper-evident guarantees that achieve both mathematical rigor and computational efficiency. Our implementation addresses urgent regulatory requirements for AI system transparency and auditability. The framework integrates with current AI governance standards, specifically the EU's AI Act and FDA's healthcare AI guidelines, enabling organizations to maintain operational efficiency while meeting compliance requirements. Testing on financial institution data demonstrated Meta-Sealing's capability to reduce audit timeframes by 62% while enhancing stakeholder confidence by 47%. Results can establish a new benchmark for integrity assurance in enterprise AI deployments. This research presents Meta-Sealing not merely as a technical solution, but as a foundational framework ensuring AI system integrity aligns with human values and regulatory requirements. As AI continues to influence critical decisions, provides the necessary bridge between technological advancement and verifiable trust. Meta-Sealing serves as a guardian of trust, ensuring that the AI systems we depend on are as reliable and transparent as they are powerful.