Prompt injection attacks, where untrusted data contains an injected prompt to manipulate the system, have been listed as the top security threat to LLM-integrated applications. Model-level prompt injection defenses have shown strong effectiveness, but the strongest defenses are proprietary. Open-source secure models are needed by the AI security community so that co-development of attacks and defenses through open research can drive scientific progress in mitigating prompt injection attacks. To this end, we develop Meta SecAlign, the first fully open-source LLM with built-in model-level defense that achieves commercial-grade performance and is powerful enough for complex agentic tasks. We provide complete details of our training recipe. We perform the most comprehensive evaluation to date on 9 utility benchmarks (measuring general knowledge, instruction following, and agentic workflows) and 7 security benchmarks. Results show that Meta SecAlign, despite being trained only on generic instruction-tuning samples, surprisingly confers security in unseen downstream tasks, including tool-calling and web-navigation, in addition to general instruction-following. Our best model -- Meta-SecAlign-70B -- establishes a new frontier of utility-security trade-off for open-source LLMs, and is more secure than several flagship proprietary models with prompt injection defense. Below are links for the code (https://github.com/facebookresearch/Meta_SecAlign), Meta-SecAlign-70B (https://huggingface.co/facebook/Meta-SecAlign-70B), and Meta-SecAlign-8B (https://huggingface.co/facebook/Meta-SecAlign-8B) models.