E-resources are inevitable, technology has grown and libraries are also adopting the technologies although adopting have many challenges to the library professionals. Whenever something new comes they need to update themselves. A study investigated E-Resources management and management issues of Indian library professional perspectives. For this study, data was collected from various academic institutes/university libraries in India. It includes institutes of national importance, central, state, deemed and private universities. The study finds that the majority of the libraries subscribed to E-journals and E-books, administration related challenges faced by LIS professionals. The t-test results revealed a lack of professional skills is the reason for issues and challenges of Library management.