In this paper, we design secure multi-party computation (MPC) protocols in the asynchronous communication setting with optimal resilience. Our protocols are secure against a computationally-unbounded malicious adversary, characterized by an adversary structure $\mathcal{Z}$, which enumerates all possible subsets of potentially corrupt parties. Our protocols incur a communication of $\mathcal{O}(|\mathcal{Z}|^2)$ and $\mathcal{O}(|\mathcal{Z}|)$ bits per multiplication for perfect and statistical security respectively. These are the first protocols with this communication complexity, as such protocols were known only in the synchronous communication setting (Hirt and Tschudi, ASIACRYPT 2013).