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How Grey’s Anatomy Season 22 Finale Ended: Meredith Grey’s Major Milestone & Truth About Character Deaths
Olivia Evans · 2026-05-08 · via E! Online (US) - Top Stories

Will Kevin McKidd Ever Return After Grey's Anatomy Exit? He Says…

It’s not a Post-It, but it’ll do.  

Luckily for fans, the Grey’s Anatomy season 22 finale did not include any major character deaths, despite Kim Raver and Kevin McKidd’s exits. 

However, Ellen Pompeo’s Dr. Meredith Grey did something perhaps more shocking than any hospital explosion or plane crash: She followed her heart. 

At the beginning of the episode, Dr. Nick Marsh (Scott Speedman) is revealed to have been part of the same bridge collapse as Owen (McKidd). 

In an intense moment in the ER, Meredith confirms to Dr. Cass Beckman (Sophia Bush) that Nick is her “husband,” to which Nick pokes fun at her in a moment of levity. 

"I'm your husband?" Nick asked Meredith, to which she said back, "That's what you're focusing on right now?"

Nevertheless, with her boyfriend of four years on the brink of death and in need of emergency surgery, Meredith grapples with not only the possibility of losing him—but also the painful memory trigger of losing late husband Dr. Derek Shepherd (Patrick Dempsey) to “incompetent surgeons,” as her sister-in-law Dr. Amelia Shepherd (Caterina Scorsone) put it.

Indeed, Meredith convinces Dr. Miranda Bailey (Chandra Wilson) to ignore her IRB ban from surgery to operate on Nick, as she is the only one she trusts. 

Once Nick is out of a successful surgery, Meredith does something she previously said she’d never do. 

"Marry me," she asked Nick, to which he joked, "How badlly was I hurt?" 

To which Meredith replied, "About enough to think about all the people that I've lost, and I really don't want to lose you."

As she put it, "It turns out, me not being married to you has not protected me from anything and I love you and I love our life together and I don't want my fear to get in the way of that anymore."

And while Meredith admitted she does not want a traditional wedding, Nick immediately accepted her proposal. 

"Are you kidding me?" Nick asked her, going on to refer to the surgery Meredith performed back in season 14, "I've wanted to marry you since the last time I was in this bed."

The moment is especially touching, as Nick has alluded to wanting to marry Meredith for several seasons—while Meredith has opted to prioritize her independence, career and kids. 

Anne Marie Fox/Disney via Getty Images

In fact, during season 20, Meredith turned down Nick when he brought up the idea of marriage. 

“I don’t know that I can marry you,” she told him in the season’s ninth episode. “I did that once before, I don’t know if I can do it again. But I love you so much.”

Meanwhile, Meredith and Nick weren't the only couple to have a sweet end to the season. Owen and Teddy (Raver) finally chose each other—and Paris. After Owen successfully saved a family from the wreckage of the bridge collapse, he not only encouraged Teddy to take her research job, but told her he’ll join her. 

“It shows a good amount of evolution and growth on Owen’s part,” McKidd told E! News of the characters’ ending in a recent interview. “To say, ‘You know it’s your time now. You’re going to have this opportunity that you’re going to go and pursue and I can’t live without you and I’m going to be there and I’m going to be by your side supporting you.’” 

As he put it, “It feels right.”

For more shocking Grey’s Anatomy moments, keep reading… 

ABC

From Booty Call to Boss

Incoming surgical intern Meredith Grey (Ellen Pompeo) was thrown for quite a loop in Grey's Anatomy's series premiere when she learned that the hunky one-night-stand she picked up at the bar played by Patrick Dempsey was actually her new boss, renowned surgeon Dr. Derek Shepherd. Oops.

ABC

Addison's Arrival

Fans were just as stunned as poor Meredith in the season one finale when Addison Montgomery (Kate Walsh) waltzed into Seattle Grace and right up to Mer and Derek, introducing herself with the now iconic "You must be the woman who's been screwing my husband."

Peter "Hopper" Stone/Walt Disney Television via Getty Images

Bombs Away

When Grey's Anatomy was given the plum post-Super Bowl slot in its second season, fans watched tensely as Meredith decided to shove her hand into a body cavity containing a live explosive to keep it from detonating. And just as we began to breathe a sigh of relief when bomb squad chief Dylan (guest star Kyle Chandler) began to walk away with the removed explosive, it blew, taking the poor guy out in the process. 

Scott Garfield/Disney General Entertainment Content via Getty Images

Denny's Demise

Fans watched as Izzie (Katherine Heigl) fell in love with the effortlessly charming Denny Duquette (Jeffrey Dean Morgan) as he awaited a much-needed heart transplant throughout the second half of season two, falling for him right along with her. And when her wild plan to cut his LVAD wire to move him up the transplant list failed spectacularly, resulting in his death in the season finale, it was confirmed that Grey's Anatomy was not here to give us the happy endings we wanted.

ABC

Meredith's Near-Death Experience

What was more surprising during season three's big ferry accident: Meredith nearly drowning after being knocked into freezing cold waters at the accident site or her later admission that she'd given up trying to survive?

ABC

Lexie's Arrival

At the end of season three, a surgical intern named Lexie (Chyler Leigh) arrived at Seattle Grace, first meeting Derek the night prior to starting at the hospital in a moment that mirrored his first interaction with Mer two seasons prior (but, thankfully, did not end with them sleeping together) and then introducing herself to George O'Malley (T.R. Knight) in the intern locker room. Oh, and her last name? Why, Grey, of course. And just like that, Meredith's younger half-sister, one of two daughters raised by her father Thatcher and his second wife Susan, was added to the mix.

ABC

Ghost Denny

Two and a half seasons after he'd perished, Denny was back and his ghost was...having sex with Izzie. In one of the most ludicrous moments in the show's history, Ghost Denny was used to signal to viewers and to Izzie herself that something was wrong. That something was ultimately proven to be stage IV metastatic melanoma, which had spread to, among other places, her brain.

ABC

It's George

While fans were expecting Izzie to bite the bullet in the season five finale, the fact that no one could find George should've clued us into the fact that something was up with poor O'Malley. When Meredith finally realized what the John Doe who'd been hit by a bus while trying to save a woman on the street was writing in her hand--007, his cruel nickname in earlier seasons--she tried to alert the surgeons working on him, but it was too late. He flatlined and died.

ABC

The Shooting

File this one under: The mist disturbing episode in Grey's history. In the season six finale, the grieving husband of a deceased patient arrived at the hospital, fresh off its merger with neighboring Mercy West, with a loaded gun and nothing left to live for. A few doctors were murdered, several more injured, and the image of Bailey (Chandra Wilson) being dragged by her feet out from under a patient's bed will forever haunt us. Thankfully, she survived. Mer and Derek's baby wasn't so lucky. After he was shot, she believed he'd died and had a traumatic miscarriage.

ABC

The Plane Crash

Two seasons after the horrific hospital shooting, Shonda Rhimes decided it was time to torture a handful of docs yet again. In the eighth season finale, a plane carrying Meredith, Derek, Cristina Yang (Sandra Oh), Lexie, Mark Sloan (Eric Dane) and Arizona Robbins (Jessica Capshaw), traveling to Boise, Idaho to perform surgery on conjoined twins, crashed in the wilderness, leaving them stranded and wounded, with no one at home even knowing they'd gone down. The accident claimed Mark and Lexie's lives and Arizona's leg, while nearly leaving Derek's hand permanently injured.

ABC

Burke's Return

How would Grey's send off Mer's person Cristina at the end of season 10 after Sandra Oh decided to move on? Why, by having ex Preston Burke (Isaiah Washington) pop back up after leaving her at the altar in season three to offer her his hospital in Switzerland. That the show brought Washington back after his highly contentious exit, which involved him referring to co-star T.R. Knight by a heinous gay slur, was truly surprising.

ABC

Maggie's Arrival

As the show said goodbye to Cristina in the season 10 finale, it welcomed her replacement as the head of cardio-thoracic surgery, Dr. Maggie Pierce. And when the character, played by Kelly McCreary, revealed to Richard (James Pickens Jr.) in the episode's final moments that she was Dr. Ellis Grey's daughter, asking if he knew the legendary doctor, he wasn't the only one stunned to learn that he had a daughter and that Mer had another sister.

ABC/Kelsey McNeal

Derek's Departure

Literally no one saw it coming when, with a handful of episodes left to air in season 11, Derek was killed off, the victim of a head-on collision just after rescuing a family on the side of the road involved in a car crash of their own. Patrick Dempsey had just recently extended his contract on the show, making his departure truly unexpected. Killing off Mer's husband may have been Shonda Rhimes' only feasible option to get rid of the character in a way that didn't render an 11-year love story completely worthless, but that didn't mean it hurt any less.

ABC

Meredith's Attack

As if Mer hadn't been through enough up to this point, in the ninth episode of season 12, she was violently attacked by a patient in a brutal episode that saw her jaw broken and then wired shut in order to restore her hearing. Her panic attack when her kids won't see her during her recovery was a stunning moment of acting from Ellen Pompeo.

ABC

Alex's Departure

How would the show explain Alex Karev's sudden absence after original star Justin Chambers walked away from his role midway through season 16? By having him write letters to wife Jo (Camilla Luddington), Mer and Bailey explaining that he'd gotten in contact with Izzie years after she ghosted and sent him divorce papers, only to learn that she'd been raising their twins all these years on a farm somewhere and he'd chosen his newfound family over his life in Seattle. If anyone tells you they saw that coming, we'll show you a liar.

ABC

The Death of Dr. DeLuca

In season 17, fans watched as Dr. Andrea "Andrew" DeLuca (Giacomo Gianniotti) met his untimely end. After overcoming his mental health struggles, DeLuca found himself as an attending at Grey Sloan Memorial Hospital. Yet, in typical Grey's fashion, Dr. DeLuca's back-on-track life was cut tragically short when he was stabbed by a human trafficker's accomplice.

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