For those seeking dramatic improvement to fine lines and wrinkles, a doctor’s appointment is nice to have—but it’s not necessarily a must-have. Some of the best wrinkle fillers are still available to those who can’t manage a visit with a top dermatologist or a facial plastic surgeon (after all, Kris Jenner’s is in high demand).
According to Shannon Humphrey, MD, founder and medical director of Humphrey & Beleznay Cosmetic Dermatology in Vancouver, “Topical wrinkle fillers can work, but it’s important to understand how they work and what they can realistically achieve.” As Humphrey explains, the products can improve the appearance of wrinkles through three mechanisms: hydration (via ingredients such as hyaluronic acid), film-forming or tightening technology (which often involves silica, silicates, or polymers), or blurring through light-diffusing particles.
“It's also worth recognizing that there is a separate category of ingredients that support skin quality over time,” Humphrey says. “Retinoids remain the gold standard among those. Peptides, growth factors and other regenerative ingredients may also help improve the appearance of wrinkles through longer-term biological mechanisms.”
Overall, Humphrey says that consumers should view topical wrinkle fillers as “appearance-enhancing products,” while keeping in mind that they cannot achieve the same degree of correction as injectables or energy-based treatments. Put another way, “Topical products do not restore volume beneath the skin, and can not provide any meaningful ‘lift,’” says Donald B. Yoo, MD, a board-certified facial plastic surgeon and the medical director at HALO Beverly Hills Plastic Surgery & Medspa.
What these creams and serums can do, however, is improve skin hydration, which temporarily improves texture, tone, and the appearance of fine lines. What’s more, the over-the-counter products can complement and preserve the results of professional treatments—and many of the newer formulas contain cutting-edge ingredients that may support greater skin health over time.
Ahead, find the best wrinkle fillers to flood the skin with hydration, boost collagen production, and deliver other benefits that can allay the return of wrinkles between appointments.
Celimax
Medik8
L'Oréal
SkinMedica
Shiseido
111Skin
Dr. Dennis Gross
Revision Skincare
Ourself
ProX by Olay
La Prairie
Do wrinkle fillers really work?
“Topical wrinkle products can be highly effective adjuncts [to professional treatments]—particularly those that support hydration, collagen remodeling, and extracellular matrix regeneration,” Dr. Gould says. “Topical wrinkle fillers don’t paralyze muscle or physically restore volume like injectables do, but they do improve skin elasticity, reduce superficial lines, and preserve a youthful appearance when used consistently.”
Which wrinkle filler is best?
Below, Dr. Ntonis breaks down the types of products that can best step in to fill wrinkles between injectable appointments.
What ingredients should you look for in a wrinkle filler?
According to Dr. Gould, the ingredients below represent the gold standards for plumping and smoothing wrinkles between appointments:
Can similar results to Botox and filler be achieved at home?
“No topical can replace the biomechanical action of neuromodulators or the structural volume provided by dermal fillers,” Dr. Gould says. “But topicals can significantly prolong results, minimize the appearance of dynamic and static wrinkles, and enhance overall skin health, especially when paired with in-office treatments and at-home devices like red-light therapy or microneedling.”
How long do wrinkle fillers last?
“Most topical wrinkle fillers work on the surface of the skin, so their effects are temporary, usually a few hours, maybe a full day if your skin is well hydrated and you’re layering them right,” Dr. Khalifian says. “But the beauty of them is that you see results almost immediately, which is exactly what some of my patients want before a big event or when their skin is feeling tired or dry.”
When we test and review a product, we take a holistic approach to deliver well-rounded product recommendations. First, we lean on Vogue’s vast network of experts—from board-certified dermatologists to celebrity makeup artists—to learn about the industry’s standout products (and they ones they’d actually use and recommend). We pair their expertise with our editorial best practices to curate the thoughtful edits you read on our site. When it comes to SPF testing, we consider texture, ease of application, ingredients, finish, and wear time all key components of our review. Read more about our testing methodology here.
When we test and review a product, we take a holistic approach to deliver well-rounded product recommendations. First, we lean on Vogue’s vast network of experts—from board-certified dermatologists to celebrity makeup artists—to gain professional acumen on the industry’s standout products, ones these specialists would actually use on their clients. We pair their expertise with our editorial best practices to curate the thoughtful edits you read on our site. To do this, we paired our own personal tests of each formula with regard to ingredients, texture and feel, ease of application, and visible results. Read more about our testing methodology here.
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