The dream of achieving glass skin doesn’t have to be unattainable—and it can be achieved with this Mizon peptide serum. The K-beauty brand’s viral formula is known for plumping skin and blurring pores with each application.
“This serum works as a multi-layer hydration and barrier-support serum that is particularly helpful for dry or dehydrated skin because it combines humectants and peptides in one formula,” says nurse practitioner Tama Tran, NP-C. The seven different peptides are the particular draw of this formula. “Combining multiple peptides can be beneficial because different peptides serve different biological roles. Peptides act as signaling molecules in the skin, instructing cells to perform functions like collagen production, inflammation reduction, or barrier repair,” board-certified dermatologist Dr. Sejal Shah, MD, tells Vogue. That said, both experts note that more peptides don’t necessarily mean better, as product formulation and concentration play huge roles in efficacy.
Even still, this serum remains a cult-favorite, with reviews and TikTokers swearing by its fast-acting hydration and balancing benefits—all while being non-comedogenic and fragrance-free.
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In this specific serum, the peptides are designed to work synergistically, targeting multiple pathways involved in aging and skin quality at once,” Dr. Shah explains. “This formula addresses dry skin through a multi-layered hydration strategy rather than relying on a single moisturizing ingredient.” She continues that the blend of classic humectants like glycerin, alongside mixed molecular-weight hyaluronic acid, help penetrate more deeply into the skin’s dermis. Meanwhile, allantoin, niacinamide, and the blend of peptides reduce transepidermal water loss. With that in mind, Dr. Shah explains that the formula doesn’t just add moisture; it also helps the skin retain hydration more effectively.
Not only does the serum refresh dull skin immediately upon application, but the results are cumulative with consistent use; Mizon’s peptide serum, in fact, progressively optimizes the skin’s receptivity. “Using this booster serum as a first step not only hydrates directly, but improves the absorption and performance of subsequent skin-care products layered afterward,” says Dr. Shah.
Meanwhile, the multi-peptide formula helps to impart multi-targeted benefits—and thereby keep product layering more streamlined. “A multi-peptide approach can be beneficial because different peptides may signal different skin functions such as collagen support, repair signaling, or calming inflammation pathways,” says Tran. “The peptide complex in the formula supports skin signaling pathways involved in repair and resilience, which can indirectly improve texture and smoothness as the barrier becomes healthier.”
How We Tested
When we test and review a product, we take a holistic approach to deliver well-rounded product recommendations. First, we lean on Vogue’s vast network of experts—from board-certified dermatologists to nurse practitioners—to gain professional acumen on the industry’s standout products, ones these specialists would actually use on their clients. We pair their expertise with our editorial best practices to curate the thoughtful edits you read on our site.
As it relates to peptide serums we selected the best based on the following characteristics: ingredients, texture, and the skin-care concerns they address. To do this, we paired our own personal tests of each formula with expert guidance and reviewer insights to determine which we would recommend to you.
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