This historic 19th-century Greenwich Village townhouse at 80 W. Washington Place — once rented by Travis Scott while he was still together with ex Kylie Jenner and, later, the scene of an alleged underground gambling den involving NBA stars — just got an A-list makeover from star interior designer Cheryl Eisen’s IMG luxury design firm.

(Neither Jenner nor Scott were mentioned in the federal indictment and sources say Scott had moved out long before the allegations surfaced.)

On the market for a hefty $21 million (down from $22.5 million last year), the Georgian red-brick townhouse is listed on the National Register of Historic Places.

At 8,757 square feet, the approximately 22-foot-wide home features six bedrooms, six baths and three powder rooms, along with four landscaped terraces.

Built in 1839, the home was once owned by famed composer John Philip Sousa and, separately, novelist Willa Cather.

“We intentionally chose a palette of restrained elegance that respects the building’s structural DNA,” Eisen, CEO and founder of IMG, tells Gimme Shelter. “We envisioned each of the six floors to be a fully realized, livable space.”

Design details include floating wood stairs with a glass banister, a skylit media lounge with a 700-bottle glass wine cellar, a bar and tasting room, a chef’s kitchen and a double-height great room with a gas fireplace and floor-to-ceiling glass doors that open to a landscaped garden.

There’s also a mezzanine that could work as a home office or library.

The home features a full-floor main bedroom suite with a private terrace, windowed dressing room and spa bath; a wellness level with a gym and glass-enclosed sauna; and outdoor space that includes a roof terrace with a bar, grill and skyline views.

The listing broker is Melissa Olson of Douglas Elliman.