惯性聚合 高效追踪和阅读你感兴趣的博客、新闻、科技资讯
阅读原文 在惯性聚合中打开

推荐订阅源

Martin Fowler
Martin Fowler
A
About on SuperTechFans
让小产品的独立变现更简单 - ezindie.com
让小产品的独立变现更简单 - ezindie.com
aimingoo的专栏
aimingoo的专栏
T
The Blog of Author Tim Ferriss
IT之家
IT之家
罗磊的独立博客
博客园_首页
月光博客
月光博客
freeCodeCamp Programming Tutorials: Python, JavaScript, Git & More
Last Week in AI
Last Week in AI
OSCHINA 社区最新新闻
OSCHINA 社区最新新闻
量子位
Hugging Face - Blog
Hugging Face - Blog
G
Google Developers Blog
博客园 - 叶小钗
H
Help Net Security
N
Netflix TechBlog - Medium
B
Blog
Engineering at Meta
Engineering at Meta
Cyber Security Advisories - MS-ISAC
Cyber Security Advisories - MS-ISAC
V
V2EX
Vercel News
Vercel News
博客园 - 三生石上(FineUI控件)

New York Post

Federal officials order flight cuts at Chicago O’Hare to reduce airport delays Minnesota dad who shoved Turning Point USA journalist at anti-ICE protest says family is 'absolutely not violent' Former adult film star Asia Carrera makes career turn after passing Texas bar exam to become attorney Boy, 13, stabbed with large knife during suspected dispute near NYC park Over 200 swarm Atlanta intersection in illegal street takeover roaring with cars racing and doing donuts Yankees' Aaron Boone blasts 'overly sensitive' umpires after first ejection of season Stream It Or Skip It: 'Fake Profile' Season 3 On Netflix, Another Crazy Season Of The Steamy Colombian Thriller Eastbound 105 Freeway reopens hours after man shot as mystery deepens around what happened Tony Bradley believes Hawks need to hit Knicks 'in the mouth first' A quiet change at a Sacramento school is raising concerns among parents Washington state teacher flashed topless pics to class full of students during PowerPoint presentation Knicks looking to push NBA-best clutch success to its limit in playoffs Stream It Or Skip It: 'Beef' Season 2 On Netflix, Where A Young Couple Take On Their Boss And His Wife When They Witness A Vicious Argument Footage shows D4vd arrested surrounded by gun-wielding cops Acting ICE Director Todd Lyons resigns after 20 years with agency -- will stay on for transition 'Proof' review: Ayo Edebiri and Don Cheadle star in underpowered Broadway revival Federal authorities issue warning after multiple drone sightings above Coors Field Ohio State dominant school at receiver with latest star set for NFL draft 'The Pitt' Season 2 Ending Explained: Does Baby Jane Doe Save Dr. Robby? SoCal man's bittersweet reunion with stolen 1969 Camaro caught on camera Dem rising star boasts about Fed experience -- but record tells different story Luka Doncic spotted in Europe at Real Madrid basketball game with tennis superstar Pregnant Aubrey Plaza flaunts her baby bump in floral minidress at NYC screening ‘The Pitt’ Season 2 Episode 15 Recap: 100 Percent F**ked Up (Season 2 Finale) ‘Shahs of Sunset’ star Mercedes ‘MJ’ Javid reveals how she found a fresh start amid divorce Deonte Banks gets Giants 'clean slate' at critical point in his NFL career Mets can't hide behind the numbers — they're feeling the pressure Tiffany & Co. Blue Book 2026 launch: Mariah Carey, Naomi Watts, Teyana Taylor and more Hannah Einbinder Couldn't Stop Bawling While Jesse McCartney Was On Set Filming 'Hacks' Episode 2: "I Cried Every Single Take" The PGA Tour reunions that must happen with LIV Golf on life support
68-year-old woman's arms and legs turn blue after taking ...
Reda Wigle · 2026-05-08 · via New York Post

Willy Wonka’s Violet Beauregarde could start a support group.

According to a case report in the New England Journal of Medicine, a 68-year-old woman developed “blue-gray hyperpigmentation” on her limbs just a couple of weeks after she started taking a common medication.

The woman sought treatment after dark patches on her arms and legs persisted for six weeks.

Collage of a patient's forearms and legs with confluent erythematous papules and plaques.
Prior to the dark development, the woman, who suffers from rosacea, a common skin condition that causes the face to appear red or flushed, began taking 100 mg daily of oral minocycline.

The woman suffers from rosacea, a common skin condition that causes the face to appear red or flushed — and wasn’t the cause of the blue hue.

“Rosacea is a chronic inflammatory condition in which the skin appears inflamed along with evidence of acne-like bumps and textural change,” dermatologist Alicia Zalka previously told The Post.

“Because the condition is multifaceted and is the result of the interplay of genetics, environment, vascular inflammatory responses of the skin, and even skin mites, there is no single cause of rosacea and similarly no single treatment,” she continued.

To treat it, she began taking 100 mg daily of oral minocycline two weeks prior.

According to the Mayo Clinic, minocycline, a tetracycline antibiotic that kills bacteria or prevents their growth, is commonly prescribed to treat the acne-like bumps associated with rosacea.

The drug — which is sold under brand names including Dynacin, Minocin and Solodyn — is widely prescribed to fight several conditions including acne and bacterial infections, like those that cause pneumonia.

A recent study found that it may also be helpful in treating panic disorder in patients who don’t respond to psychiatric medications, including benzodiazepines like clonazepam.

Minocycline’s side effects include dizziness, GI issues like nausea, headache, fatigue and skin sensitivity.

Collage of a woman's arms and legs exhibiting blue-gray discoloration due to medication.
After six months, the hyperpigmentation had “abated somewhat” but had not completely faded, as seen in the before-and-after photos. The New England Journal of Medicine

But hyperpigmentation — which can cause the skin to turn blue-grey or blue-black — is rare, impacting only affects 3-15% of patients. And it typically develops over months of treatment, not weeks.

For this woman, the dark patches were initially isolated to her legs and described as “asymptomatic.”

It ultimately presented on her forearms and the sides of her tongue as well, leading to a diagnosis of “minocycline-induced hyperpigmentation.”

Medical staff urged the woman to stop taking the medication and avoid sun exposure. After six months, the hyperpigmentation had “abated somewhat” but had not faded completely.

While the woman was diagnosed with Type II minocycline-induced hyperpigmentation, in which the skin turns blue or gray, there are three additional types.

For patients with Type I, blue-black spots appear in scar tissue, for those with Type III, muddy brown spots develop in areas of the skin exposed to sunlight, and for those with Type IV, these muddy brown spots appear in scar tissue.

Experts maintain that patients should be warned of the risk of these skin changes, which can necessitate laser treatments to remove.

In addition to the hyperpigmentation described above, minocycline can cause other serious skin reactions, including erythema multiforme and Stevens-Johnson syndrome (SJS), a rare disorder that begins with flu-like symptoms followed by a rash that blisters and spreads.

The condition is fatal in 10% of patients.

Minocycline has been used in humans for more than 50 years and is generally considered safe.