“Danny Go!” star Daniel Coleman’s son Isaac has died. He was 14 years old.

The YouTuber announced his eldest child’s passing in a heartbreaking statement via Instagram Friday.

“Oh my sweet boy,” he began. “There’s so much I want to say, but I don’t know how yet. I already miss you so much, and the pain in my heart is far more than I can process. But looking through thousands of pictures and videos this past week, I’m also filled with tremendous pride.”

The influencer, who also shares son Levi with wife Mindy Coleman, added, “Your 14 years were full of so many challenges, but you met them all with such grit … and you somehow kept your trademark joy in spite of it all. You truly had a spark like no other, Isaac!

“Remembering how loved you were and how full of life your time here was gives me great comfort,” he concluded. “Being your dad was the honor of a lifetime. I’m so proud of you and I love you forever. Rest peacefully, son.”

In December 2025, Daniel revealed Isaac’s Stage 3 mouth cancer diagnosis.

“We found out last week that Isaac has cancer in his mouth. TBH, we always knew this day was coming, as it’s a near certainty [with] Fanconi anemia,” he told his Instagram followers at the time.

Fanconi anemia is a rare, inherited condition that affects bone marrow and other parts of the body, per the Cleveland Clinic, and individuals with it have an increased risk of developing blood disorders and some kinds of cancer.

Daniel, however, noted that Isaac’s diagnosis was “definitely hitting a little earlier than [they] hoped and [was] still just such a shocking thing to hear about your child, even if you’ve braced for it for years.”

He continued, “Been getting lots of scans and we’re not sure yet how much it’s spread.”

The family had hoped they’d be able to “remove the cancer surgically,” but in February, Daniel revealed that due to several Fanconi-related complexities, Isaac’s treatment options were “much more limited than in typical pediatric cancer.”

That same month, Daniel canceled the remainder of his “Danny Go!” tour as Isaac’s condition worsened.

Last month, he gave the devastating update that the teen had entered hospice care as their family focused on Isaac’s “comfort.”

“Mindy and I are heartbroken watching him decline, knowing how frustrating and scary this must be for him,” Daniel wrote. “But we’re trying to hold it all together & keep soaking up the time we still have with our boy.”

His “Danny Go!” YouTube channel launched in 2021 and has since grown to more than 4.5 million subscribers.