For the last few years, it seems like Ozempic has been the main drug calling the shots in weight loss.
But now, some health experts — and hordes of social media users — are predicting a new wave of supplements might start carrying the weight. They’re calling it the “Fauxzempic” era.
Fauxempic or fake-Ozempic mainly refers to drugs falsely advertised as delivering GLP-1–like effects, but the term is also used more widely for the influx of GLP-1 boosters and activators entering the market as “natural” and drug-free alternatives, promising everything from increased fat burn and improved gut health to better regularity — and, of course, weight loss.
According to data from Grand View Research, the global weight-loss supplement market was valued at $33.14 billion in 2024 and is projected to surge to $71.59 billion by 2030, growing at an annual rate of 14.17% between 2025 and 2030.
“There has been a significant increase in supplements marketed as ‘natural GLP-1 activators’ or alternatives,” explained nutritionist and Wellness the Right Way founder Katelyn Bedford, who holds a master’s degree in dietetics and nutrition and is certified in weight management.
Many viral brands like Lemme, HUM Nutrition, Love Wellness and Sakara Life have all entered the market with their own versions of metabolism boosters and GLP-1 support supplements.
Bedford acknowledges that many of the key ingredients are rooted in science, but they don’t work quite like a GLP-1.
“These products often rely on ingredients like fiber, berberine, or green tea extract, which may have modest metabolic effects, but do not replicate the mechanism or effectiveness of GLP-1 medications.”
Bedford, whose company specializes in weight-loss counseling and consulting, said she has seen growing interest in these products among clients. However, she warned that many GLP-1 activators are “often under-regulated and overpromised” and that the “claims are often misleading.”
“Supplements are not regulated at the same level as medications, so quality, dosing, and safety can vary widely,” Bedford explained. “Patients should be cautious of proprietary blends, exaggerated marketing language and products promising rapid or effortless weight loss.”
If someone does choose to try a GLP-1 activator, Bedford recommends closely scrutinizing whether the formula is clinically backed and selecting a trusted brand that is third-party tested. And ultimately, Bedford still recommends implementing sustainable, evidence-based strategies over relying on supplements.
“Nutritionally, this includes prioritizing protein intake (generally around 1.2–1.6 grams per kilogram of body weight) to support satiety and preserve lean mass, along with adequate fiber intake to help regulate appetite and blood sugar,” she advises.
Bedford also recommends pairing a balanced diet with daily movement, and suggests integrating easy at-home workout equipment and fitness tracking to support her clients and keep them accountable.
Find more of Bedford’s suggestions for incorporating practical tools that can support weight loss below.
When it comes to weight-loss support supplements, Bedford suggests looking for a straightforward berberine supplement from a high-quality brand.
She points to a meta-analysis that showed a significant reduction in body weight, BMI and waist circumference associated with berberine intake — all of which may also play an indirect role in improving metabolic health.
“Thorne has solid third-party testing, and they’re also allergen-friendly,” Bedford explained. “This formula combines two different berberine extracts: 450 milligrams of the well-studied berberine HCl, as well as 550 milligrams of berberine phytosome, which is believed to aid absorption.”
Bedford also recommends that her clients look for a clean protein powder.
Several studies have shown that eating a high-protein diet can be an effective and safe tool for weight reduction, while also helping prevent obesity and obesity-related diseases.
The key, Bedford says, is supplementing with protein powders that cut out unnecessary ingredients while still tasting good enough to build into your routine. Truvani is one she personally recommends.
“It uses high-quality, clean ingredients without unnecessary additives, which aligns well with a holistic approach to nutrition,” Bedford noted. “It’s a convenient way to help clients meet protein needs for satiety, muscle maintenance, and weight management — especially for those with busy lifestyles.”
Bedford also emphasizes the importance of nourishing a healthy gut microbiome, which can help regulate hunger hormones and support digestion, both of which are key factors in weight management. Prebiotic fiber acts as “food” for beneficial gut bacteria, helping to create a more balanced ecosystem.
An article published in 2020 found that prebiotic fiber may help improve risk factors associated with obesity, concluding that “prebiotic fibers have the ability to alter the gut microbiota in a positive manner, indicating their promise as a dietary treatment.”
Bedford recommends a blend from Garden of Life, which produces five grams of fiber per serving, all derived from nutrient-dense superfoods, such as cacia, orange peel, apple peel and cranberry fruit.
“This prebiotic fiber supplement is helpful for supporting gut health, which plays a key role in weight regulation, digestion and overall wellness. I often suggest fiber support for clients who struggle to meet daily intake through food alone, as it can also improve fullness and stabilize blood sugar,” she noted.
“Structured meal prep is one of the most practical behavior-change strategies for weight management,” emphasized Bedford, who recommends using meal-prep containers to portion out meals.
One study found that more frequent meal planning was associated with better weight loss outcomes in a worksite-based behavioral weight loss program. Participants who planned their meals more often experienced greater weight loss, even more so than those who focused on exercise planning frequency.
“These containers help clients stay consistent with portion control, reduce reliance on takeout, and make balanced eating more convenient during a busy week,” Bedford added.
For those working towards weight loss goals, the Mayo Clinic recommends getting at least 150 minutes of moderate aerobic activity a week, or about 75 minutes of vigorous aerobic activity a week.
Bedford also stresses that exercise shouldn’t be forgotten in the equation — and fortunately, there are plenty of simple at-home workout tools that can add intensity and get your heart rate up, no expensive classes or gym membership required. Bala Bangles are one of her favorites.
“These are a great way to subtly increase daily energy expenditure without requiring a full workout session,” explained Bedford. I like them for clients who are building consistency with movement, as they can elevate walks or everyday activities in an approachable, non-intimidating way.”
Many weight loss experts have also turned to wearable fitness trackers to help patients keep track of their goals and progress. However, the data on these newer devices is still relatively limited.
One systematic review found “some evidence that wearable devices can improve long-term physical activity and weight loss outcomes, but there was not enough evidence to show a benefit over the comparator methods.”
Regardless, Bedford believes the Fitbit is a valuable tool that provides users with all sorts of data, from step count to stress levels and sleep quality. The app also offers some more advanced coaching tips.
“A great tool to track activity and stay on top of goals associated with weight loss,” said Bedford. “Great way to visibly see progress through activity.”
Bedford says she is consistently steering patients away from extreme or unsustainable diet approaches.
“This includes very low-calorie ‘GLP-1 mimic’ diets, which attempt to replicate medication effects through severe restriction; these often result in muscle loss, nutrient deficiencies and metabolic slowdown,” she noted.
She adds that detoxes and cleanses remain popular and ‘trendy’, but are not evidence-based and can lead to inadequate protein intake and blood sugar instability.
Before starting a GLP-1 medication, Bedford emphasizes that it’s a tool, and not a replacement for long-term lifestyle change.
“Patients need to be prepared to build sustainable nutrition and exercise habits alongside the medication to maintain results long-term,” she explained. “I also counsel patients on the importance of maintaining adequate protein intake, hydration and micronutrient status, as appetite suppression can significantly reduce overall intake.”
She adds that screening is important as well, particularly for individuals with a history of eating disorders, gastrointestinal conditions, gallbladder disease or certain thyroid cancers.
“The most common side effects I see clinically include nausea, constipation, early satiety and fatigue. One of the biggest concerns from a nutrition standpoint is unintended muscle loss if protein intake and resistance training are not prioritized,” said Bedford.
From a clinical standpoint, Bedford recommends choosing supplements that have third-party testing (such as NSF Certified for Sport or USP verification).
She also cautions people to consult their physicians prior to starting a new supplement and check for potential interactions with any current medications.
“Most importantly, supplements should support, not replace, foundational nutrition and lifestyle strategies,” she stressed.
For patients not using GLP-1 medications, Bedford focuses on sustainable, evidence-based strategies — including prioritizing protein intake and getting adequate fiber.
“Rather than extreme restriction, I recommend a modest calorie deficit paired with high-volume, nutrient-dense foods like vegetables, fruits and lean proteins,” she notes. “Behaviorally, consistency is key. Structured meals, adequate sleep and stress management all play a significant role.”
From an exercise standpoint, she says resistance training is essential, as “this helps preserve muscle mass and supports metabolic health during weight loss.” She also encourages increasing daily movement and adding cardiovascular exercise as a complement rather than the primary focus.
This article was written by Miska Salemann, New York Post Commerce Writer/Reporter. As a health-forward member of Gen Z, Miska seeks out experts to weigh in on the benefits, safety and designs of both trending and tried-and-true fitness equipment, workout clothing, dietary supplements and more. Taking matters into her own hands, Miska intrepidly tests wellness products, ranging from Bryan Johnson’s Blueprint Longevity Mix to the viral Oura Ring to Jennifer Aniston’s favorite workout platform – often with her adorable toddler by her side. Before joining The Post, Miska covered lifestyle and consumer topics for the U.S. Sun and The Cannon Beach Gazette.
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