X marks the spot — and scientists have finally drawn the map.

For nearly three decades, researchers have had a detailed understanding of the nerve network that makes up the penis. But when it came to the organ responsible for female pleasure, they were largely flying blind. 

Now, a groundbreaking study has finally charted out those elusive sensory pathways, a breakthrough that experts say could have far-reaching implications, including helping surgeons preserve sexual function in women undergoing pelvic operations.

Considered one of the least studied organs in the human body, the clitoris has long been shrouded in cultural taboos, which has hindered research into this pleasure center of female reproductive anatomy.

Despite references dating back to ancient times, it didn’t appear in standard anatomy textbooks until the 20th century. When it was finally included in what many consider the leading “doctors’ bible” in 1995, it was described simply as a “small version of the penis.”

But it turns out the organ is far larger and more complex than the pea-sized nub at the top of the vulva often associated with sexual arousal and orgasm.

In the study, Dutch researchers used high-energy X-ray imaging to create detailed 3D scans of the pelvic regions of two deceased women who donated their bodies to science.

The scans revealed that the main sensory nerve running to the clitoris doesn’t simply taper off, as older anatomical models suggested. Instead, it splits into several branches, forming a tree-like network inside and around the pleasure organ. 

“This is the first-ever 3D map of the nerves within the glans of the clitoris,” Dr. Ju Young Lee, a study author and research associate at Amsterdam University Medical Center in the Netherlands, told The Guardian. 

A comparable map of the male anatomy was created back in 1998.

The findings could be especially significant for survivors of female genital mutilation (FGM), a practice that involves the partial or total removal of external female genitalia.

The procedures, carried out mostly on young girls and teens, affect more than 230 million women around the globe.

The World Health Organization classifies FGM as a human rights violation. It can also lead to serious medical complications, including bleeding, infections, urinary problems and complications during childbirth — not to mention reduced sexual pleasure.

While reconstructive surgeries exist that aim to restore clitoral function after mutilation, nearly a quarter of women still report a decline in orgasmic experience after the procedure.

“Our study provides the anatomical foundation necessary to investigate the physiological mechanism behind these sensory changes and potentially refine the surgical technique,” the authors wrote.

The imaging could also help improve outcomes in other procedures, including genital cosmetic surgeries and operations to repair damage from childbirth.

By better understanding the anatomy of the clitoris, for example, it could help doctors avoid damaging delicate nerve pathways that extend throughout the vulva.

“We have peripheral nerve treatments for everything else from head to toe, but the genital region is like a black box that’s been unexplored,” Dr. Blair Peters, an associate professor of surgery in the Oregon Health and Science University (OHSU) School of Medicine, who wasn’t involved in the study, told LiveScience.

“This anatomic work is super important to better treat a lot of medical conditions that for the most part have very limited options.”

The development is the latest in a string of discoveries in recent years involving an organ that belongs to nearly half the world’s population.

Back in 2022, Peters and his colleagues at OHSU found that the clitoris contains more than 10,000 nerve fibers on average — about 25% more than previously estimated.

Looking ahead, the study authors say future research should focus on the specific functions of the complex nerve system they mapped for the first time.

Because both pelvic scans used in the study came from postmenopausal women, the researchers also want to conduct similar imaging across other age groups.

“It opens the door, but we need larger studies to really understand the full picture,” Alexandra Dubinskaya, a urogynecologist at Cedars-Sinai Urology who did not participate in the study, told Smithsonian magazine.

“As a field, bringing this kind of knowledge into everyday practice and education has real potential to change how we care for women.”